Cost-Effectiveness of High- and Low-Osmolality Contrast Media in Patients with High Risk of Contrast Induced Nephropathy

Documento FCE No EAECP-4

15 Pages Posted: 4 Dec 2009 Last revised: 22 Feb 2011

See all articles by Oscar Gamboa

Oscar Gamboa

Instituto Nacional de Cancerología - Servicio de Radioterapia

Liliana Chicaíza

Escuela de Administración de Empresas y Contaduría Pública

Mario García Molina

National University of Colombia - Department of Economics

Date Written: December 3, 2009

Abstract

Contrast media induced nephropathy is a common cause of kidney failure in hospitalized patients. It has been suggested that high-osmolality contrast media caused less nephropathies than low-osmolality ones. The cost-effectiveness of High- (Iodixanol) and Low-osmolality (Iohexol, Iopamidol and others) contrast media are compared by means of a decision tree. The analysis showed that Iopamidol and Iodixanol strategies dominated all the others. The incremental cost-effectiveness ratio of Iodixanol compared to Iopamidol is $31.637.306 per adicional avoided nephropathy. Iodixanol strategy is cost-effective for a budget per patient higher than $980.000, or 50 ml vial cost lower than $57.000, or willingness to pay per nephropathy avoided higher than $32.000.000.

Keywords: Cost-effectiveness, Health, Health care, Kidney failure, Contrast media

JEL Classification: D610, I110

Suggested Citation

Gamboa, Oscar and Chicaíza, Liliana and García Molina, Mario, Cost-Effectiveness of High- and Low-Osmolality Contrast Media in Patients with High Risk of Contrast Induced Nephropathy (December 3, 2009). Documento FCE No EAECP-4, Available at SSRN: https://ssrn.com/abstract=1517879 or http://dx.doi.org/10.2139/ssrn.1517879

Oscar Gamboa (Contact Author)

Instituto Nacional de Cancerología - Servicio de Radioterapia ( email )

Calle 1 No. 9-85
Bogotá
Colombia

HOME PAGE: http://www.incancerologia.gov.co/

Liliana Chicaíza

Escuela de Administración de Empresas y Contaduría Pública ( email )

Carrera 30 45-03
Bogota, None
Colombia

Mario García Molina

National University of Colombia - Department of Economics ( email )

Carrera 30 Calle 45 Ciudad Universitaria
Bogotá
Colombia

HOME PAGE: http://www.unal.edu.co

Do you have negative results from your research you’d like to share?

Paper statistics

Downloads
39
Abstract Views
521
PlumX Metrics