Cost-Effectiveness of High- and Low-Osmolality Contrast Media in Patients with High Risk of Contrast Induced Nephropathy
Documento FCE No EAECP-4
15 Pages Posted: 4 Dec 2009 Last revised: 22 Feb 2011
Date Written: December 3, 2009
Abstract
Contrast media induced nephropathy is a common cause of kidney failure in hospitalized patients. It has been suggested that high-osmolality contrast media caused less nephropathies than low-osmolality ones. The cost-effectiveness of High- (Iodixanol) and Low-osmolality (Iohexol, Iopamidol and others) contrast media are compared by means of a decision tree. The analysis showed that Iopamidol and Iodixanol strategies dominated all the others. The incremental cost-effectiveness ratio of Iodixanol compared to Iopamidol is $31.637.306 per adicional avoided nephropathy. Iodixanol strategy is cost-effective for a budget per patient higher than $980.000, or 50 ml vial cost lower than $57.000, or willingness to pay per nephropathy avoided higher than $32.000.000.
Keywords: Cost-effectiveness, Health, Health care, Kidney failure, Contrast media
JEL Classification: D610, I110
Suggested Citation: Suggested Citation