The Change Level of Concentration of Hsp70 in the Different Age in the Goats in Various Seasons

Abstract

Difference of ability of breed/animal at tolerance of heat stress, the HSP70 effective is one of the major as a cellular thermometer in response to heat stress. Even estimate the ability of a specifically breed/ animal for heat stress, it is pressing to determine its thermo tolerance ability. Heat shock proteins (HSPs) are molecular chaperons that preserve domestic conformation of proteins and cell viability in the stress condition. The peripheral blood mononuclear cells (PBMCs) ubiquitous have been used as a cellular model for explained the differential heat shock reactive toward livestock species. The current research was aimed with the pretension that seasonal difference cause the alterations in the level of concentration HSP70, on other hand investigation in change concentration level of HSP70 in the different (1 year and 2 years) in the goats for Alpine and Saanen breeds. The average concentration of HSP70 was higher (26.9, 18.34 and 14.7) for Saanen breed in the spring, summer and the winter respectively as respect to Alpine breed. In compassion to goats in the age of 1 year and goats in the age of 2 years relative concentration level of HSP70 showed significant increase HSP70 in the age of 1 year and during different seasons (spring, summer and winter) with significantly (p<0.01).generally the study concluded, Saanen goat in the different age shown difference in their ability to ameliorate the mischievous effect of heat stress therefore as to preserve cellular integrity.

Keywords: HSP70; Saanen; Alpine; Season; Age; Stress