A Brief Study on Motor Neuron Disease; and Its Treatment Includes Drug Delivery System; Future Aspects on Neurological Science

Abstract

Motor neuron disease is vary hazards disease in recent time, MND (Motor Neuron Disease) basically it shows clinical presentation to ALS (Amyotrophic lateral sclerosis) considered is most neurodegenerative disease. In MND basically loss of nerves in the spine and brain is not working so it is Refferd to neurodegeneration. It is recorded as in last past year we have seen lots of changes related to patient care treatment improving and drug safety but also rapid scientific advances is there, so that rational therapies based on key pathogenic mechanisms now seem plausible. ALS have both properties in heterogeneous. it occurs 1 year to delay from first symptoms to diagnosis where as half of patient succumb within 3-4 years , although the heterogeneity suggest therapeutic study with respect to clinical study. RNA Process is also implicated and show protein degradation. Apparent clinical heterogeneity tells us that therapeutic studies should include detailed biomarker profiling, they even tell us about the genetic and clinical statistritions. The most common mutation, accounting for 10% of all Western hemispheres ALS due to this protein degradation is occurs. Major part is still not clear how these fundamental is working continuously. This pre- symptomatic study considered is new era or new initiative for neurodegenerative disorders in neurological sciences.

Keywords: Neurodegenerative disease, RNA, Amyotrophic lateral sclerosis, neurological sciences.