Impact of COVID-19 on Pregnancy and Childbirth: A Systematic Literature Review of Recent Evidence

20 Pages Posted: 8 Jun 2020

See all articles by Mir Ibrahim Sajid

Mir Ibrahim Sajid

Aga Khan University, Medical College

Shehar Bano Awais

Aga Khan University, Medical College

Khizar Salar

Aga Khan University, Medical College, Students

Maryam Sherwani

Aga Khan University, Medical College, Students

Nighat Kamal

Dr Zia-Ud-Din Hospital

Zahida Parveen

Ayub Medical College

Date Written: May 11, 2020

Abstract

Aim: To evaluate the pathogenesis, risk factors, diagnosis and management strategies in pregnant women suspected or confirmed with COVID-19 infection.

Methods: A literature review of published articles was carried out using keywords of corona virus (and its root derivatives), pregnancy, vertical transmission and childbirth in Medline, Cochrane, CINAHL, Clinicaltrials.gov and Web of Sciences. Clinical articles including case-control, case reports, case series and reviews published between 2019 and 2020, in English language were included. Editorials and Letter to Editors were not included. Two independent authors reviewed title and abstract of the articles and another set of two independent authors screened full text. A total of 22 articles were shortlisted for addition into the final manuscript

Results: A total of 403 pregnancies were considered in the study with most of the patients in the third trimester of pregnancy. There was no maternal mortality reported in the literature, however 1.49% fetal mortality has been reported.

Conclusion: The ideal management revolves around, rapid detection, prompt diagnosis and effective isolation.

Note: Funding: No funding was received by any author or author’s institute in development of this manuscript

Conflict of Interest: All the authors confirm that there is no conflict of interest associated with the production of this 392manuscript

Keywords: COVID-19, Pregnancy, Childbirth

Suggested Citation

Sajid, Mir Ibrahim and Awais, Shehar Bano and Salar, Khizar and Sherwani, Maryam and Kamal, Nighat and Parveen, Zahida, Impact of COVID-19 on Pregnancy and Childbirth: A Systematic Literature Review of Recent Evidence (May 11, 2020). Available at SSRN: https://ssrn.com/abstract=3598547 or http://dx.doi.org/10.2139/ssrn.3598547

Mir Ibrahim Sajid (Contact Author)

Aga Khan University, Medical College ( email )

Karachi
Pakistan

Shehar Bano Awais

Aga Khan University, Medical College

Karachi
Pakistan

Khizar Salar

Aga Khan University, Medical College, Students

Karachi
Pakistan

Maryam Sherwani

Aga Khan University, Medical College, Students

Karachi
Pakistan

Nighat Kamal

Dr Zia-Ud-Din Hospital ( email )

Shahrah-e-Ghaleb Road, Clifton
Karachi, 74880
Pakistan

Zahida Parveen

Ayub Medical College ( email )

N-35
Abbottabad, 22040
Pakistan

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